Adam ZR,  Kacar B, Som SS, Lynch K, Walther-Antonio M, Williford K. The origin of animals as microbial host volumes in nutrient-limited seas (submitted) 



Adam ZR, Fahrenbach AC, Kacar B, Aono M. Prebiotic geochemical automata at the intersection of radiolytic chemistry, physical complexity, and systems biology Complexity, 2018,

(White paper) Domagal-Goldman S. et al. Life Beyond the Solar System: Remotely Detectable Biosignatures Astrobiology, 2018, arXiv:1801.06714v1

Walker SI, Bains W, Cronin L, DasSarma S, Danielache S, Goldman SD, Kacar B & others.  Exoplanet Biosignatures: Future Directions Astrobiology, 2018(6)


Kacar B‡, Hanson-Smith V, Adam ZR, Boekelheide N. 2017 Reconstruction and Dynamic Modeling of Ancestral Rubisco Proteins Geobiology, 00:113. (Covered in New Scientist, NASA Astrobiology Institute Research Highlights

Kacar B‡, Guy L, Smith E, Baross J. 2017 Resurrecting ancestral genes in bacteria to interpret ancient biosignatures Roy Soc Phil Trans A, 2017;375(2109) doi: 10.1098/rsta.2016.0352.

Kacar B‡*Garmendia E*, Tuncbag N, Andersson DI, Hughes D. 2017 Functional Constraints on Replacing an Essential Gene with Its Ancient and Modern Homologs MBio, 8(4)  doi: 10.1128/mBio.01276-17.

Kacar B, Ge X, Sanyal S, Gaucher EA. 2017 Experimental evolution of Escherichia coli harboring an ancient translation protein J Mol Evol, 84(2-3):69-84  doi:10.1007/s00239-017-9781-0. (Journal Cover) (MicroJC Discussion video) (Covered in SciWorthy)

2016 – previous

Kacar B  Rolling the Dice Twice: Evolving Reconstructed Ancient Proteins in Extant Organisms Chance in Evolution eds. Pence & Ramsay, University of Chicago Press 2016, 265-276 

Kacar B. Astrobiology Primer 2.0 What is LUCA? Domagal-Goldman S, Wright K et al,. 2016 Astrobiology 16(8):561-653 

Kacar B. Horak R.Astrobiology Primer 2.0, What does the tree of life tell us about how life has evolved? Domagal-Goldman S, Wright K et al,. 2016 Astrobiology 16(8):561-653 

Kacar B and Gaucher EA. 2013, Biochem J, 453(3), 311-319 Experimental evolution of protein-protein interaction networks (Covered in Quanta)

Kacar B and Gaucher EA. 2012, Artificial Life, 13, 11-18 Towards the recapitulation of ancient history in the laboratory: Combining synthetic biology with experimental evolution (Covered in Wired, MIT Tech ReviewPopular Science, BBC, iO9 and more)

Kacar B, Boyd ES, Dolci W, Dodson E, Boldt M, Pilcher CB. 2011, PLoS Biology, 9(8):e1001118  Workshop without walls: Broadening science access around the world

Aldeco M*, Kacar B*, Edmondson D.E. 2011, Comp. Biochemistry, 159(2):78-83 Catalytic and Inhibitor Binding Properties of Zebrafish Monoamine Oxidase (zMAO): Comparisons with human MAO A and MAO B

Kacar B, and Edmondson D.E. 2010, Protein. Exp. Purif., 70(2):290-297  Expression of Zebrafish (Danio rerio) Monoamine Oxidase (MAO) in Pichia pastoris: Purification and Comparison with Human MAO A and MAO B

(*Equal contribution, Corresponding author)

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